future

The Human Genome Project

FUTURE

The Human Genome Project was, and still is, expected to bring advancements in biology and medicine. Pharmacogenomics is expected to be expanded by using the information from this project to "lower toxicity through tailoring drug treatment to individual, genetically determined differences in drug metabolism" (National Institute of Medicine). The project is foreseen to bring out advances in diagnosis and treatments of cancer as scientists can examine genomic changes in an individual tumor with this breakthrough. The National Institutes of Health reports that the HGP helps with discoveries and treatments of rare mutations we couldn’t even dream of fixing before breaking the genetic mapping barrier.

Two example cases are the Kentucky family and the Breery twins. 

(Scientist, picfair.com)

Breery Twins: 

(Breery Twins, youtube.com)

As their diagnosis worsened, the help of genome sequencing helped the family figure out what exactly was wrong and led to the twins being correctly treated.

Kentucky Family: 

Several members of a Kentucky family were found to have a rare mutation causing a narrowing of leg arteries. Genomic analyses showed a mutation involving the gene NT5E, which dealt with calcium metabolism. Researchers are now developing therapeutic approaches to help treat this rare mutation.

(Vericose veins, mayoclinichealthsystem.org)